image bio

Get an extra 10% off your first month of any subscription with code SEPT23. Shop Now

Earn up to $500 when you refer friends to Natalist. Learn More

Home > Learn > Nutrition > >Folate and PCOS

Folate and PCOS

Apr 20, 20 2 min
Folate and PCOS - Natalist

A recent study showed that folate has beneficial effects on metabolic profiles in women with PCOS. Registered Dietitian Nicole Holovach explains what you need to know.

By Nicole Holovach, Registered Dietitian

For the majority of the population, folic acid and folate are the same thing—a nutrient found in food and prenatal vitamins that helps prevent neural tube defects in babies. While the terms are often used interchangeably, there is an important distinction between the two. Folate is a B vitamin found in foods like dark leafy greens, lentils, beans, eggs, sunflower seeds, and liver. Folic acid is the synthetic form of folate. It is only found in fortified foods and supplements and must be converted to the active form within the cell. Humans are unable to make their own folate, so we have to get it from food or supplements.

Most prenatal vitamins contain folic acid because it’s less expensive, more stable, and more of it is absorbed than folate. But there are several factors that affect conversion of folic acid to the active form. Under normal dietary conditions, absorbed folic acid is converted into an active form used by the body. Age, environmental factors, a defect in the converted gene, and certain drugs can all play a part in how effectively folic acid is converted.

In certain clients, I may have them switch to a prenatal with folate, or add a folate supplement, depending on their health issues. For my clients with polycystic ovary syndrome (PCOS), I now have a reason to potentially add a folate supplement.

💊 Shop Folate ⟶

How does folate benefit women with PCOS?

A recent study showed that folate, the active form, has beneficial effects on metabolic profiles in women with PCOS. The study was a randomized controlled trial, considered the “gold standard” of research. In the study, 5 mg of folate supplementation, compared with 1 mg and a placebo, resulted in better glucose metabolism and better cholesterol lab values in women with PCOS.

The average prenatal vitamin has between 600-1000mcg (1 mg) of folic acid or folate, so to reach 5 mg another supplement may be needed. While there is little risk associated with folate supplementation, it is recommended to speak with your physician before taking folate for PCOS or any other supplement. They may recommend considering a myo-inositol supplement to improve PCOS symptoms. Check out this blog on the benefits of inositol for more information.

 

This piece was contributed by a guest writer for Shady Grove Fertility, a leading fertility and IVF center of excellence. SGF offers patients individualized care, innovative financial options, over 30 accepted insurance plans, and pregnancy rates among the highest of all national centers. SGV has 19 full-service and 6 satellite locations across Maryland, Pennsylvania, Virginia, and Washington, D.C.

Shop Products From This Article
methylated folate supplement product and packaging

MTHF Folate

Extra 10% off your first delivery when you subscribe with code SEPT23

$25

sticker new
menstrual cycle regulation support

Cycle Support Bundle

Bundle & save on cycle regularity support‡

$85 $75

Shop Products

sticker new
Myo and D Chiro Inositol supplement capsules

Inositol Plus

Extra 10% off your first delivery when you subscribe with code SEPT23

$35

Subscribe & Save $3.00 sticker new
Natalist-hydration-energy-electrolyte-drink-mix

Hydration & Energy Electrolyte Drink Mix

Extra 10% off your first delivery when you subscribe with code SEPT23

$32

sticker favorite
Natalist Ovulation Test Kit

Ovulation Test Kit

As low as $0.76 per strip

$25

Subscribe & Save $6.00 sticker new
Box of Natalist Hydration & Energy mix next to Magnesium Plus bottle

Drink Mix Duo

Extra 10% off your first delivery when you subscribe with code SEPT23

$70 $59

sticker bestseller
Front of Natalist Prenatal Daily Packets against a white background

Prenatal Daily Packets

Extra 10% off your first delivery when you subscribe with code SEPT23

$60

Subscribe & Save $15.00 sticker favorite
Prenatal Daily Packets Trimester Pack

Trimester Pack: Prenatal Daily Packets

Extra 10% off your first delivery when you subscribe with code SEPT23

$180 $150

sticker bestseller
Prenatal gummy vitamins

Prenatal Gummies

Extra 10% off your first delivery when you subscribe with code SEPT23

$35

Subscribe & Save $10.00 sticker favorite
Trimester Pack: Prenatal Gummies

Trimester Pack: Prenatal Gummies

Extra 10% off your first delivery when you subscribe with code SEPT23

$105 $85

sticker bestseller
Pregnancy Tests (4-Count)

Pregnancy Tests (4-Count)

As low as $3.20 per test

$16

sticker favorite
Natalist Ovulation Test Kit

Ovulation Test Kit

As low as $0.76 per strip

$25

sticker favorite
Women's Fertility Test Bundle

Women's Fertility Test Bundle

Bundle & save $26

$205 $185

sticker save
The Test Strip Pack

The Test Strip Pack

Bundle & save with our earth-friendlier test strips

$37